Efficient one-pot synthesis of 1-aryl 1,2,3-triazoles from aryl halides and terminal alkynes in the presence of sodium azide

被引：78

作者：

Andersen, J

Bolvig, S

Liang, XF

机构：

[1] Leo Pharmaceut Prod, Dept Med Chem, DK-2750 Ballerup, Denmark

[2] Leo Pharmaceut Prod, Dept Spect & Phys Chem, DK-2750 Ballerup, Denmark

来源：

SYNLETT | 2005年 / 19期

关键词：

1,2,3-triazoles; one-pot; copper; 1,3-dipolar cycloaddition; catalyst;

D O I：

10.1055/s-2005-921887

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient one-pot synthesis of 1-aryl 1,2,3-triazoles from aryl bromides/iodides and terminal alkynes in the presence of sodium azide is described. In the case of aryl iodides, the reactions proceeded at room temperature. The reactions normally gave high yields.

引用

收藏

页码：2941 / 2947

页数：7

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