A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria

被引：207

作者：

Feng, Guangxue ^{[1
,2
]}

Yuan, Youyong ^{[1
]}

Fang, Hu ^{[3
]}

Zhang, Ruoyu ^{[1
]}

Xing, Bengang ^{[4
]}

Zhang, Guanxin ^{[3
]}

Zhang, Deqing ^{[3
]}

Liu, Bin ^{[1
,5
]}

机构：

[1] Natl Univ Singapore, Dept Chem & Biomol Engn, Singapore 117576, Singapore

[2] Natl Univ Singapore, Environm Res Inst, Singapore 117411, Singapore

[3] Chinese Acad Sci, Organ Solids Lab, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China

[4] Nanyang Technol Univ, Div Chem & Biol Chem, Singapore 637371, Singapore

[5] Inst Mat Res Engn A STAR, Inst Mat Res & Engn, Singapore 117602, Singapore

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 62期

基金：

新加坡国家研究基金会;

关键词：

VANCOMYCIN-RESISTANT ENTEROCOCCI; ULTRABRIGHT ORGANIC DOTS; BLOOD CULTURE BOTTLES; ALA-D-ALA; IN-VITRO; STAPHYLOCOCCUS-AUREUS; BACILLUS-SUBTILIS; CANCER-CELLS; THERAPY; NANOPARTICLES;

D O I：

10.1039/c5cc03807c

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

We report the design and synthesis of a red fluorescent AIE light-up probe for selective recognition, naked-eye detection, and image-guided photodynamic killing of Gram-positive bacteria, including vancomycin-resistant Enterococcus strains.

引用

收藏

页码：12490 / 12493

页数：4

相关论文

共 63 条

[1]

SINGLET OXYGEN FORMATION IN MONOMERIC AND AGGREGATED PORPHYRIN-C [J].

BENNETT, LE ;

GHIGGINO, KP ;

HENDERSON, RW .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 1989, 3 (01) :81-89

[2]

Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity [J].

Boisselier, Elodie ;

Astruc, Didier .

CHEMICAL SOCIETY REVIEWS, 2009, 38 (06) :1759-1782

[3]

The structure of VanX reveals a novel amino-dipeptidase involved in mediating transposon-based vancomycin resistance [J].

Bussiere, DE ;

Pratt, SD ;

Katz, L ;

Severin, JM ;

Holzman, T ;

Park, CH .

MOLECULAR CELL, 1998, 2 (01) :75-84

[4]

Vancomycin-resistant enterococci [J].

Cetinkaya, Y ;

Falk, P ;

Mayhall, CG .

CLINICAL MICROBIOLOGY REVIEWS, 2000, 13 (04) :686-+

[5]

Infection with vancomycin-resistant Staphylococcus aureus containing the vanA resistance gene [J].

Chang, S ;

Sievert, DM ;

Hageman, JC ;

Boulton, ML ;

Tenover, FC ;

Downes, FP ;

Shah, S ;

Rudrik, JT ;

Pupp, GR ;

Brown, WJ ;

Cardo, D ;

Fridkin, SK .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (14) :1342-1347

[6]

Identification of Bacteria in Water by a Fluorescent Array [J].

Chen, Wenwen ;

Li, Qizhai ;

Zheng, Wenshu ;

Hu, Fang ;

Zhang, Guanxin ;

Wang, Zhuo ;

Zhang, Deqing ;

Jiang, Xingyu .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (50) :13734-13739

[7]

Recent advances in organic mechanofluorochromic materials [J].

Chi, Zhenguo ;

Zhang, Xiqi ;

Xu, Bingjia ;

Zhou, Xie ;

Ma, Chunping ;

Zhang, Yi ;

Liu, Siwei ;

Xu, Jiarui .

CHEMICAL SOCIETY REVIEWS, 2012, 41 (10) :3878-3896

[8]

Chung HJ, 2013, NAT NANOTECHNOL, V8, P369, DOI [10.1038/nnano.2013.70, 10.1038/NNANO.2013.70]

[9]

Detection of infectious and toxigenic bacteria [J].

Deisingh, AK ;

Thompson, M .

ANALYST, 2002, 127 (05) :567-581

[10]

Transforming clinical microbiology with bacterial genome sequencing [J].

Didelot, Xavier ;

Bowden, Rory ;

Wilson, Daniel J. ;

Peto, Tim E. A. ;

Crook, Derrick W. .

NATURE REVIEWS GENETICS, 2012, 13 (09) :601-612

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