Identification of Bacteria in Water by a Fluorescent Array

被引：180

作者：

Chen, Wenwen ^{[1
,2
,3
]}

Li, Qizhai ^{[4
]}

Zheng, Wenshu ^{[1
,2
,3
]}

Hu, Fang ^{[3
,5
]}

Zhang, Guanxin ^{[5
]}

Wang, Zhuo ^{[1
,2
]}

Zhang, Deqing ^{[5
]}

Jiang, Xingyu ^{[1
,2
]}

机构：

[1] Natl Ctr NanoSci & Technol, Beijing Engn Res Ctr BioNanotechnol, Beijing 100190, Peoples R China

[2] Natl Ctr NanoSci & Technol, Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China

[3] Univ Chinese Acad Sci, Beijing 100190, Peoples R China

[4] Chinese Acad Sci, Acad Math & Syst Sci, Beijing 100190, Peoples R China

[5] Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci Organ Solids Lab, Beijing 100190, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2014年 / 53卷 / 50期

基金：

北京市自然科学基金; 中国国家自然科学基金;

关键词：

bacteria; biosensors; fluorescent probes; mathematical analysis; AGGREGATION-INDUCED EMISSION; VITEK-2; COMPACT; SENSOR ARRAY; RAPID IDENTIFICATION; CONJUGATED POLYMERS; MALDI-TOF; BLOOD; NANOPARTICLES; DIFFERENTIATION; PERFORMANCE;

D O I：

10.1002/anie.201407606

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

We report a method for the rapid and efficient identification of bacteria making use of five probes having fluorescent characteristics (F-array) and subsequent statistical analysis. Eight kinds of bacteria, including normal and multidrug-resistant bacteria, are differentiated successfully. Our easy-to-perform and time-saving method consists of mixing bacteria and probes, recording fluorescent intensity data by automated flow cytometry, and statistical analysis. No washing steps are required in order to identify the different bacteria simultaneously.

引用

页码：13734 / 13739

页数：6

共 61 条

[1]

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[2]

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[3]

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