Synthesis and characterization of water-soluble two-photon excited blue fluorescent chromophores for bioimaging

被引:44
作者
Hayek, A
Bolze, F
Nicoud, JF
Baldeck, PL
Mély, Y
机构
[1] CNRS, Inst Phys & Chim Mat Strasbourg, UMR 7504, Grp Mat Organ, F-67034 Strasbourg, France
[2] Univ Grenoble 1, CNRS, UMR 5588, Spectrometrie Phys Lab, F-38402 St Martin Dheres, France
[3] Fac Pharm, CNRS, UMR 7034, F-67401 Illkirch Graffenstaden, France
关键词
D O I
10.1039/b509843b
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We report here the synthesis and characterization of a new type of non-ionic blue fluorescent water-soluble chromophores specifically designed for two-photon absorption microscopy. The water solubility is induced by introduction of short oligo( ethylene glycol) monomethyl ether moieties. This work has led to low molecular weight dyes with efficient two-photon absorption cross sections and high fluorescence quantum yield in organic solvents as well as in aqueous solutions.
引用
收藏
页码:102 / 106
页数:5
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