A New Route to gamma-Arylidenebutyrolactones via a tandem carbopalladation-heterocyclisation sequence: A formal synthesis of U-68,215.

被引：45

作者：

Cavicchioli, M ^{[1
]}

Decortiat, S ^{[1
]}

Bouyssi, D ^{[1
]}

Gore, J ^{[1
]}

Balme, G ^{[1
]}

机构：

[1] UNIV LYON 1,CNRS,LAB CHIM ORGAN 1,CPE LYON,F-69622 VILLEURBANNE,FRANCE

来源：

TETRAHEDRON | 1996年 / 52卷 / 35期

关键词：

D O I：

10.1016/0040-4020(96)00637-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Benzo-annulated enol lactones are obtained in good yields from pentynoic acids 3- or 5-substituted with an iodo-aryl moiety by palladium-catalyzed cyclization of their potassium carboxylates. Using this approach, an efficient new route to U-68,215 is described. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：11463 / 11478

页数：16

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