Microbial interactions in the vaginal ecosystem, with emphasis on the pathogenesis of bacterial vaginosis

被引：82

作者：

Pybus, V ^{[1
]}

Onderdonk, AB

机构：

[1] Harvard Univ, Sch Med, Channing Lab, Boston, MA 02115 USA

[2] Brigham & Womens Hosp, Boston, MA 02115 USA

[3] Beth Israel Deaconess Med Ctr, Div Infect Dis, Boston, MA 02215 USA

[4] Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA

[5] Harvard Univ, Sch Med, Inst Med, Boston, MA 02215 USA

来源：

MICROBES AND INFECTION | 1999年 / 1卷 / 04期

关键词：

bacterial vaginosis; microbial interactions; vagina; hydrogen peroxide;

D O I：

10.1016/S1286-4579(99)80024-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

During bacterial vaginosis (BV), populations of lactobacilli which are generally dominant in the vagina of overtly healthy women are replaced by other facultative and anaerobic microorganisms. Some Lactobacillus strains produce hydrogen peroxide and all produce lactic acid; however, the antagonistic role of these metabolites in vivo remains controversial. Positive interactions among BV-associated organisms may contribute to the pathogenesis of BV and its sequelae. (C) Elsevier, Paris.

引用

页码：285 / 292

页数：8

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