Asperger syndrome: a simple matter of white matter?

被引:40
作者
Ellis, HD [1 ]
Gunter, HL [1 ]
机构
[1] Univ Cardiff, Sch Psychol, Cardiff CF1 3YG, S Glam, Wales
关键词
D O I
10.1016/S1364-6613(99)01315-7
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Asperger syndrome, one of the Pervasive Developmental Disorders, is formally diagnosed on the basis of a cluster of cognitive, social and motor signs. It is also associated with poor visuo-spatial skills, good verbal performance, gauche social behavior and clumsiness, Many of the difficulties evident in those with Asperger syndrome are closely associated with right-hemisphere dysfunction, In this respect they also resemble signs used to diagnose what has been labelled Nonverbal Learning Disorder. Here, these are treated as being the same or closely-related disorders; with a possible common underlying aetiology; that is, a neurodevelopmental abnormality affecting white matter. This review examines the ability of this approach to account for a wide range of characteristics of the Asperger syndrome, and contrasts this with a theory-of-mind approach, which, although able to account for the primary features of Asperger syndrome, is less successful at explaining some of its secondary features.
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页码:192 / 200
页数:9
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