Hydrophobic Anticancer Drug Delivery by a 980 nm Laser-Driven Photothermal Vehicle for Efficient Synergistic Therapy of Cancer Cells In Vivo

被引：419

作者：

Dong, Kai ^{[1
,2
,3
]}

Liu, Zhen ^{[1
,2
,3
]}

Li, Zhenhua ^{[1
,2
,3
]}

Ren, Jinsong ^{[1
,2
]}

Qu, Xiaogang ^{[1
,2
]}

机构：

[1] Changchun Inst Appl Chem, Biol Chem Lab, Changchun 130022, Peoples R China

[2] Changchun Inst Appl Chem, State Key Lab Rare Earth Resource Utilizat, Changchun 130022, Peoples R China

[3] Univ Chinese Acad Sci, Beijing 100039, Peoples R China

来源：

ADVANCED MATERIALS | 2013年 / 25卷 / 32期

基金：

中国国家自然科学基金;

关键词：

cancer therapy; drug delivery; hollow CuS nanoparticles; hydrophobic anticancer drug; synergistic therapy; MESOPOROUS SILICA NANOPARTICLES; NEAR-INFRARED LIGHT; COPPER SULFIDE NANOPARTICLES; GOLD NANORODS; ORGANIC NANOPARTICLES; INTRACELLULAR DRUG; HEMOLYTIC-ACTIVITY; CONTROLLED-RELEASE; SURFACE-CHEMISTRY; CARBON NANOTUBES;

D O I：

10.1002/adma.201301232

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

A novel 980 nm laser-driven hydrophobic anticancer drug-delivery platform based on hollow CuS nanoparticles is constructed in this work. The excellent synergistic therapy combining drug treatment and photothermal ablation of cancer cells both in vitro and in vivo is demonstrated, which opens up new opportunities for biological and medical applications. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4452 / 4458

页数：7

共 56 条

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