Chromatographic procedures for determination of cannabinoids in biological samples, with special attention to blood and alternative matrices like hair, saliva, sweat and meconium

This paper reviews chromatographic procedures for determination of cannabinoids in biological samples. Special attention was focused on blood and alternative matrices like hair, saliva, sweat and meconium. Papers published from 1998 to the early beginning of 1999 were taken into consideration. Gas chromatographic and liquid chromatographic procedures with different detectors (e.g. mass spectrometer or diode array) were considered. Basic information about the biosample assayed, sample preparation, work-up, gas chromatography column or liquid chromatography column and mobile phase, detection mode, reference and validation data are summarized in tables. (C) 1999 Elsevier Science B.V. All rights reserved.