GAS-CHROMATOGRAPHIC MASS-SPECTROMETRIC METHODS OF ANALYSIS FOR DETECTION OF 11-NOR-DELTA-9-TETRAHYDROCANNABINOL-9-CARBOXYLIC ACID IN BIOLOGICAL MATRICES

被引：14

作者：

BRONNER, WE ^{[1
]}

XU, AS ^{[1
]}

机构：

[1] HARRIS LABS INC, PHOENIX, AZ 85034 USA

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1992年 / 580卷 / 1-2期

关键词：

D O I：

10.1016/0378-4347(92)80528-X

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Gas chromatographic-mass spectrometric methods of analysis for the detection of 11-nor-DELTA9-tetrahydrocinnabinol-9-carboxylic acid, a major metabolite of DELTA9-tetrahydrocannabinol, are reviewed. Emphasis is on analytical methodology including numerous derivatization techniques developed specifically for this analyte. The majority of procedures cited in the literature were developed to detect this metabolite in the blood and urine of man.

引用

收藏

页码：63 / 75

页数：13

相关论文

共 112 条

[1] EVALUATION OF EMIT AND RIA HIGH-VOLUME TEST PROCEDURES FOR THC METABOLITES IN URINE UTILIZING GC/MS CONFIRMATION [J].

ABERCROMBIE, ML ;

JEWELL, JS .

JOURNAL OF ANALYTICAL TOXICOLOGY, 1986, 10 (05) :178-180

[2]

AGURELL S, 1986, PHARMACOL REV, V38, P21

[3] PASSIVE CONSUMPTION OF MARIJUANA THROUGH MILK - A LOW-LEVEL CHRONIC EXPOSURE TO DELTA-9-TETRAHYDROCANNABINOL (THC) [J].

AHMAD, GR ;

AHMAD, N .

JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY, 1990, 28 (02) :255-260

[4] ABERRANT RADIOIMMUNOASSAY RESULTS FOR CANNABINOIDS IN URINE [J].

ALTUNKAYA, D ;

SMITH, RN .

FORENSIC SCIENCE INTERNATIONAL, 1990, 47 (03) :195-205

[5] URINARY CANNABINOID ANALYSIS - COMPARISON OF 4 IMMUNOASSAYS WITH GAS-CHROMATOGRAPHY MASS-SPECTROMETRY [J].

ALTUNKAYA, D ;

CLATWORTHY, AJ ;

SMITH, RN ;

START, IJ .

FORENSIC SCIENCE INTERNATIONAL, 1991, 50 (01) :15-22

[6] RAPID METHOD FOR THE GC MS CONFIRMATION OF 11-NOR-9-CARBOXY-DELTA-9-TETRAHYDROCANNABINOL IN URINE [J].

BAKER, TS ;

HARRY, JV ;

RUSSELL, JW ;

MYERS, RL .

JOURNAL OF ANALYTICAL TOXICOLOGY, 1984, 8 (06) :255-259

[7]

BALABANOVA S, 1989, Z RECHTSMED, V102, P503

[8] INTERPRETATION OF URINE QUANTITATIVE 11-NOR-DELTA-9 TETRAHYDROCANNABINOL-9-CARBOXYLIC ACID TO DETERMINE ABSTINENCE FROM MARIJUANA SMOKING [J].

BELL, R ;

TAYLOR, EH ;

ACKERMAN, B ;

PAPPAS, AA .

JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY, 1989, 27 (1-2) :109-115

[9] THE DETECTION OF TETRAHYDROCANNABINOL IN BLOOD - A COMPARATIVE-STUDY [J].

BERGMAN, RA ;

LUKASZEWSKI, T ;

WANG, SYS .

JOURNAL OF ANALYTICAL TOXICOLOGY, 1981, 5 (02) :85-89

[10] GAS-CHROMATOGRAPHY OF CANNABIS CONSTITUENTS, INCLUDING CANNABINOID ACIDS, WITH ON-COLUMN ALKYLATION AND ESTERIFICATION [J].

BJORKMAN, S .

JOURNAL OF CHROMATOGRAPHY, 1982, 237 (03) :389-397

← 1 2 3 4 5 6 7 8 9 10 →