GAS-CHROMATOGRAPHIC MASS-SPECTROMETRIC METHODS OF ANALYSIS FOR DETECTION OF 11-NOR-DELTA-9-TETRAHYDROCANNABINOL-9-CARBOXYLIC ACID IN BIOLOGICAL MATRICES

被引：14

作者：

BRONNER, WE ^{[1
]}

XU, AS ^{[1
]}

机构：

[1] HARRIS LABS INC, PHOENIX, AZ 85034 USA

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1992年 / 580卷 / 1-2期

关键词：

D O I：

10.1016/0378-4347(92)80528-X

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Gas chromatographic-mass spectrometric methods of analysis for the detection of 11-nor-DELTA9-tetrahydrocinnabinol-9-carboxylic acid, a major metabolite of DELTA9-tetrahydrocannabinol, are reviewed. Emphasis is on analytical methodology including numerous derivatization techniques developed specifically for this analyte. The majority of procedures cited in the literature were developed to detect this metabolite in the blood and urine of man.

引用

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页码：63 / 75

页数：13

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