The first direct coupling of 1-trialkylsilyl-1-alkynes with vinyl triflates; a new access to enynes

被引：50

作者：

Halbes, U ^{[1
]}

Bertus, P ^{[1
]}

Pale, P ^{[1
]}

机构：

[1] Univ Strasbourg, Inst Le Bel, CNRS, Lab Synthese & React Organ, F-67000 Strasbourg, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 49期

关键词：

coupling reactions; enynes; palladium; silver; silyl; alkynes;

D O I：

10.1016/S0040-4039(01)01900-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Trialkylsilyl-1-alkynes can be directly coupled with vinyl triflates in the presence of TBAF, 3H(2)O and a catalytic amount of AgI and Pd(PPh3)(4). Functionalized enynes can thus be obtained in good to excellent yields without prior deprotection of the alkyne. (C) 2001 Published by Elsevier Science Ltd.

引用

页码：8641 / 8644

页数：4

共 24 条

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