Selective dimethyldioxirane oxidation of bile acid methyl esters

被引：11

作者：

Buxton, PC

Marples, BA ^{[1
]}

Toon, RC

Waddington, VL

机构：

[1] Univ Loughborough, Dept Chem, Loughborough LE11 3TU, Leics, England

[2] SmithKline Beecham Pharmaceut, Harlow CM19 5AW, Essex, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 25期

关键词：

D O I：

10.1016/S0040-4039(99)00834-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

DMDO oxidation of the hydroxy groups of bile acid methyl esters establishes the positional order of reactivity as 3 similar to 7 > 6 > 12 and supports a mechanism involving C-H oxygen insertion through a planar intramolecularly hydrogen bonded transition state. (C) 1999 Elsevier Science Ltd. All rights reserved.

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收藏

页码：4729 / 4732

页数：4

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