Evolutionary conservation of microtubule-capture mechanisms

被引:135
作者
Gundersen, GG [1 ]
机构
[1] Columbia Univ, Dept Anat & Cell Biol, New York, NY 10032 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1038/nrm777
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The dynamic nature of microtubules allows them to search the three-dimensional space of the cell. But what are they looking for? During cellular morphogenesis, microtubules are captured at sites just under the plasma membrane, and this polarizes the microtubule array and associated organelles. Recent data indicate that the signalling pathways that are involved in regulating the different microtubule-cortical interactions are not only conserved between species, but also that they function in diverse processes.
引用
收藏
页码:296 / 304
页数:10
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