Automated gel permeation chromatographic clean-up of human adipose tissue for multiresidue analysis of organochlorine compounds

被引:9
作者
Pauwels, A
David, F
Schepens, P
Sandra, P
机构
[1] Univ Instelling Antwerp, Toxicol Ctr Pharmaceut Sci, B-2610 Wilrijk, Belgium
[2] Res Inst Chromatog, B-8500 Kortrijk, Belgium
[3] State Univ Ghent, Dept Organ Chem, B-9000 Ghent, Belgium
关键词
adipose tissue; electron capture detector; gel permeation chromatography; organochlorine pesticides; polychlorinated biphenyls;
D O I
10.1080/03067319908032661
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Human adipose tissue samples have been analysed for organochlorine pesticides and polychlorinated biphenyls (PCBs). Following a micro liquid-solid extraction, clean-up is performed by automated gel permeation chromatography. The GPC separation provides clean extracts, allowing subsequential analysis by capillary gas chromatography-electron capture detection without additional clean-up.
引用
收藏
页码:171 / 178
页数:8
相关论文
共 29 条
[21]   Gel permeation chromatography high-performance liquid chromatography combination as an automated clean-up technique for the multiresidue analysis of fats [J].
Rimkus, GG ;
Rummler, M ;
Nausch, I .
JOURNAL OF CHROMATOGRAPHY A, 1996, 737 (01) :9-14
[22]  
Sannino A, 1996, J AOAC INT, V79, P1434
[23]   Occurrence of persistent organochlorine contaminants in human milk collected in several regions of Czech Republic [J].
Schoula, R ;
Hajslova, J ;
Bencko, V ;
Poustka, J ;
Holadova, K ;
Vizek, V .
CHEMOSPHERE, 1996, 33 (08) :1485-1494
[24]  
SCHUSTER R, 1993, 1250916241E HP
[25]   DETERMINATION OF TOXIC PCB CONGENERS IN BIOLOGICAL SAMPLES BY MULTIDIMENSIONAL GAS-CHROMATOGRAPHY MASS-SPECTROMETRY (GC/GC/MS) [J].
SIPPOLA, E ;
HIMBERG, K .
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 1991, 339 (07) :510-512
[26]  
STALLING DL, 1972, J ASSOC OFF ANA CHEM, V55, P32
[27]   Determination of organochlorine compounds in fatty matrices - Application of rapid off-line normal-phase liquid chromatographic clean-up [J].
vanderHoff, GR ;
vanBeuzekom, AC ;
Brinkman, AT ;
Baumann, RA ;
vanZoonen, P .
JOURNAL OF CHROMATOGRAPHY A, 1996, 754 (1-2) :487-496
[28]   MINIATURIZATION OF SIZE-EXCLUSION CHROMATOGRAPHY AS A POWERFUL CLEANUP TOOL IN RESIDUE ANALYSIS [J].
VANRHIJN, JA ;
TUINSTRA, LGMT .
JOURNAL OF CHROMATOGRAPHY, 1991, 552 (1-2) :517-526
[29]   DETERMINATION OF ORGANOCHLORINE PESTICIDE-RESIDUES IN HUMAN ADIPOSE-TISSUE - 1992 STUDY IN MEXICO [J].
WALISZEWSKI, SM ;
SEDAS, VTP ;
INFANZON, RM ;
RIVERA, J .
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1995, 55 (01) :43-49