Immune synapses in T-cell activation

被引：109

作者：

Cemerski, Saso ^{[1
]}

Shaw, Andrey ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2006年 / 18卷 / 03期

关键词：

D O I：

10.1016/j.coi.2006.03.011

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The contact site between T cells and antigen-presenting cells or T cells and their targets - the immunological synapse - is a highly specialized structure potentially involved in T-cell activation and function. Although many insights have been obtained since the initial description of the immune synapse, recent advances have provided us with a better understanding of mechanisms involved in synapse formation and in the diversity of synapse morphologies. New potential roles for the synapse such as in polarized cytokine secretion or in adaptive control of T-cell activation have been proposed.

引用

页码：298 / 304

页数：7

共 41 条

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