Landomycin A inhibits DNA synthesis and G1/S cell cycle progression

被引：63

作者：

Crow, RT ^{[1
]}

Rosenbaum, B

Smith, R

Guo, Y

Ramos, KS

Sulikowski, GA

机构：

[1] Texas A&M Univ, Dept Chem, College Stn, TX 77842 USA

[2] Texas A&M Univ, Dept Vet Pathobiol, College Stn, TX 77842 USA

[3] Texas A&M Univ, Dept Vet Physiol & Pharmacol, College Stn, TX 77842 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1999年 / 9卷 / 12期

关键词：

D O I：

10.1016/S0960-894X(99)00261-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Landomycin A was found to inhibit the uptake of [H-3]thymidine into DNA in murine smooth muscle cells indicating decreased DNA synthesis. Subsequent studies showed that landomycin A inhibits cell cycle progression. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1663 / 1666

页数：4

共 9 条

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