Molecular characterization of methicillin-resistant Staphylococcus epidermidis clones:: Evidence of geographic dissemination

被引：81

作者：

Miragaia, M

Couto, I

Pereira, SFF

Kristinsson, KG

Westh, H

Jarlov, JO

Carriço, J

Almeida, J

Santos-Sanches, I

de Lencastre, H

机构：

[1] Rockefeller Univ, Microbiol Lab, New York, NY 10021 USA

[2] Univ Nova Lisboa, Inst Tecnol Quim & Biol, Mol Genet Lab, P-2780 Oeiras, Portugal

[3] Univ Nova Lisboa, Inst Tecnol Quim & Biol, Biomath Lab, P-2780 Oeiras, Portugal

[4] Univ Nova Lisboa, Fac Ciencias & Tecnol, Ctr Recursos Microbiol, P-2825 Monte De Caparica, Portugal

[5] Landspitali Univ Hosp, Dept Clin Microbiol, Reykjavik, Iceland

[6] Univ Copenhagen, Hvidovre Hosp, DK-2650 Hvidovre, Denmark

[7] Herlev Hosp, Dept Clin Microbiol, DK-2730 Herlev, Denmark

[8] Med Univ S Carolina, Dept Biometry & Epidemiol, Charleston, SC 29425 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2002年 / 40卷 / 02期

关键词：

D O I：

10.1128/JCM.40.2.430-438.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Denmark and Iceland are countries where the frequency of methicillin-resistant Staphylococcus aureus is very low due to strict infection control and restrictive antibiotic use policies. In contrast, methicillin-resistant S. epidermidis (MRSE) continues to be isolated as a nosocomial pathogen. The molecular typing by pulsed-field gel electrophoresis (PFGE) of 136 MRSE isolates from five hospitals in Denmark and 94 MRSE isolates from one hospital in Iceland collected in 1997 and 1998 defined 40 different patterns. Closely related PFGE types were found in isolates recovered in Iceland, Denmark, Mexico, Uruguay, Greece, and Cape Verde, evidencing for the first time the geographic clonal dissemination of MRSE strains. The large majority (87.4%) of the MRSE isolates studied were multiresistant.

引用

收藏

页码：430 / 438

页数：9

相关论文

共 46 条

[1] DISSEMINATION AMONG STAPHYLOCOCCI OF DNA-SEQUENCES ASSOCIATED WITH METHICILLIN RESISTANCE [J].

ARCHER, GL ;

NIEMEYER, DM ;

THANASSI, JA ;

PUCCI, MJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (03) :447-454

[2] COMMUNITY-ACQUIRED BACTEREMIAS FROM TUNNELED CENTRAL INTRAVENOUS LINES - RESULTS FROM STUDIES OF A SINGLE VENDOR [J].

BROWN, RB ;

CIPRIANI, D ;

SCHULTE, M ;

CORL, A ;

PIECZARKA, R .

AMERICAN JOURNAL OF INFECTION CONTROL, 1994, 22 (03) :149-151

[3] An epidemiological study of blood culture isolates of coagulase-negative staphylococci demonstrating hospital-acquired infection [J].

Burnie, JP ;

NaderiNasab, M ;

Loudon, KW ;

Matthews, RC .

JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (07) :1746-1750

[4] Aminoglycoside resistance among Danish blood culture isolates of coagulase-negative staphylococci [J].

BuschSorensen, C ;

FrimodtMoller, N ;

Miller, GH ;

Espersen, F .

APMIS, 1996, 104 (12) :873-880

[5] Variation in antibiotic use in the European Union [J].

Cars, O ;

Mölstad, S ;

Melander, A .

LANCET, 2001, 357 (9271) :1851-1853

[6] Molecular typing of methicillin-resistant Staphylococcus aureus by pulsed-field gel electrophoresis:: Comparison of results obtained in a multilaboratory effort using identical protocols and MRSA strains [J].

Chung, M ;

De Lencastre, H ;

Matthews, P ;

Tomasz, A ;

Adamsson, I ;

De Sousa, MA ;

Camou, T ;

Cocuzza, C ;

Corso, A ;

Couto, I ;

Dominguez, A ;

Gniadkowski, M ;

Goering, R ;

Gomes, A ;

Kikuchi, K ;

Marchese, A ;

Mato, R ;

Melter, O ;

Oliveira, D ;

Palacio, R ;

Sá-Leao, R ;

Sanches, IS ;

Song, JH ;

Tassios, PT ;

Villari, P .

MICROBIAL DRUG RESISTANCE-MECHANISMS EPIDEMIOLOGY AND DISEASE, 2000, 6 (03) :189-198

[7] Identification of clinical staphylococcal isolates from humans by internal transcribed spacer PCR [J].

Couto, I ;

Pereira, S ;

Miragaia, M ;

Sanches, IS ;

de Lencastre, H .

JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (09) :3099-3103

[8] The evolution of methicillin resistance in Staphylococcus aureus:: Similarity of genetic backgrounds in historically early methicillin-susceptible and -resistant isolates and contemporary epidemic clones [J].

Crisóstomo, MI ;

Westh, H ;

Tomasz, A ;

Chung, M ;

Oliveira, DC ;

de Lencastre, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (17) :9865-9870

[9] Archaic strains of methicillin-resistant Staphylococcus aureus:: Molecular and microbiological properties of isolates from the 1960s in Denmark [J].

De Lencastre, H ;

Chung, M ;

Westh, H .

MICROBIAL DRUG RESISTANCE-MECHANISMS EPIDEMIOLOGY AND DISEASE, 2000, 6 (01) :1-10

[10] Epidemiological study of staphylococcal colonization and cross-infection in two west African hospitals [J].

De Sousa, MA ;

Sanches, IS ;

Ferro, ML ;

de Lencastre, H .

MICROBIAL DRUG RESISTANCE, 2000, 6 (02) :133-141

← 1 2 3 4 5 →