Polymer-supported lipid shells, onions, and flowers

被引：69

作者：

Bershteyn, Anna ^{[1
]}

Chaparro, Jose ^{[1
]}

Yau, Richard ^{[1
]}

Kim, Mikyung ^{[2
]}

Reinherz, Ellis ^{[2
]}

Ferreira-Moita, Luis ^{[3
]}

Irvine, Darrell J. ^{[1
]}

机构：

[1] MIT, Dept Mat Sci & Engn & Biol Engn, Cambridge, MA 02139 USA

[2] Dana Farber Canc Inst, Boston, MA 02115 USA

[3] Inst Mol Med, Cell Biol Immune Syst Unit, P-1649028 Lisbon, Portugal

来源：

SOFT MATTER | 2008年 / 4卷 / 09期

关键词：

D O I：

10.1039/b804933e

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Phospholipid-enveloped biodegradable polymer microparticles and nanoparticles synthesized by an emulsion-solvent evaporation process were characterized by confocal and cryoelectron micros-copies to show that the lipid envelope exhibits two-dimensional fluidity and can be configured into 'shell', 'onion', or 'flower' nanostructures, depending on the quantity and composition of lipids employed in the synthesis.

引用

页码：1787 / 1791

页数：5

共 44 条

[1] LIPID-COMPOSITION AND FLUIDITY OF THE HUMAN-IMMUNODEFICIENCY-VIRUS ENVELOPE AND HOST-CELL PLASMA-MEMBRANES [J].

ALOIA, RC ;

TIAN, HR ;

JENSEN, FC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (11) :5181-5185

[2] LATERAL MOTION OF FLUORESCENTLY LABELED ACETYLCHOLINE RECEPTORS IN MEMBRANES OF DEVELOPING MUSCLE-FIBERS [J].

AXELROD, D ;

RAVDIN, P ;

KOPPEL, DE ;

SCHLESSINGER, J ;

WEBB, WW ;

ELSON, EL ;

PODLESKI, TR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (12) :4594-4598

[3] Cell-directed assembly of bio/nano interfaces - A new scheme for cell immobilization [J].

Baca, Helen K. ;

Carnes, Eric ;

Singh, Seema ;

Ashley, Carlee ;

Lopez, Deanna ;

Brinker, C. Jeffrey .

ACCOUNTS OF CHEMICAL RESEARCH, 2007, 40 (09) :836-845

[4] Cell-directed assembly of lipid-silica nanostructures providing extended cell viability [J].

Baca, Helen K. ;

Ashley, Carlee ;

Carnes, Eric ;

Lopez, Deanna ;

Flemming, Jeb ;

Dunphy, Darren ;

Singh, Seema ;

Chen, Zhu ;

Liu, Nanguo ;

Fan, Hongyou ;

Lopez, Gabriel P. ;

Brozik, Susan M. ;

Werner-Washburne, Margaret ;

Brinker, C. Jeffrey .

SCIENCE, 2006, 313 (5785) :337-341

[5] The HIV lipidome:: A raft with an unusual composition [J].

Brügger, B ;

Glass, B ;

Haberkant, P ;

Leibrecht, I ;

Wieland, FT ;

Kräusslich, HG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (08) :2641-2646

[6] PHOSPHOLIPID ADSORPTION ONTO POLYSTYRENE MICROSPHERES [J].

CARMONARIBEIRO, AM ;

HERRINGTON, TM .

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1993, 156 (01) :19-23

[7] Writing and erasing barriers to lateral mobility into fluid phospholipid bilayers [J].

Cremer, PS ;

Groves, JT ;

Kung, LA ;

Boxer, SG .

LANGMUIR, 1999, 15 (11) :3893-3896

[8] Making lipid membranes rough, tough, and ready to hit the road [J].

Daniel, Susan ;

Albertorio, Fernando ;

Cremer, Paul S. .

MRS BULLETIN, 2006, 31 (07) :536-540

[9] Targeted binding of PLA microparticles with lipid-PEG-tethered ligands [J].

Duncanson, Wynter J. ;

Figa, Michael A. ;

Hallock, Kevin ;

Zalipsky, Samuel ;

Hamilton, James A. ;

Wong, Joyce Y. .

BIOMATERIALS, 2007, 28 (33) :4991-4999

[10] Relating the phagocytosis of microparticles by alveolar macrophages to surface chemistry: the effect of 1,2-dipalmitoylphosphatidylcholine [J].

Evora, C ;

Soriano, I ;

Rogers, RA ;

Shakesheff, KM ;

Hanes, J ;

Langer, R .

JOURNAL OF CONTROLLED RELEASE, 1998, 51 (2-3) :143-152

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