Primary Prevention of Atherosclerosis A Clinical Challenge for the Reversal of Epigenetic Mechanisms?

被引：108

作者：

Napoli, Claudio ^{[1
,2
]}

Crudele, Valeria ^{[1
]}

Soricelli, Andrea ^{[2
,3
]}

Al-Omran, Mohammed ^{[4
]}

Vitale, Nicoletta ^{[5
]}

Infante, Teresa ^{[2
]}

Mancini, Francesco P. ^{[5
]}

机构：

[1] Univ Naples 2, Sch Med 1,Azienda Univ Policlin, Excellence Res Ctr Cardiovasc Dis,Reg Reference L, Dept Gen Pathol,UOC Immunohematol Transfus Med &, I-80138 Naples, Italy

[2] Fdn SDN, Ist Ricovero & Cura Carattere Sci, Naples, Italy

[3] Parthenope Univ, Naples, Italy

[4] King Saud Univ, Coll Med, Peripheral Vasc Dis Res Chair, Riyadh 11461, Saudi Arabia

[5] Univ Sannio, Dept Sci Biol Geol & Environm, Benevento, Italy

来源：

CIRCULATION | 2012年 / 125卷 / 19期

关键词：

primary prevention; epigenetics; statins; CARDIOVASCULAR RISK-FACTORS; RANDOMIZED CONTROLLED-TRIAL; ABDOMINAL AORTIC-ANEURYSM; RENIN-ANGIOTENSIN SYSTEM; GENOME-WIDE ASSOCIATION; FATTY STREAK FORMATION; SMOOTH-MUSCLE-CELLS; C-REACTIVE PROTEIN; MATERNAL-HYPERCHOLESTEROLEMIA; DNA METHYLATION;

D O I：

10.1161/CIRCULATIONAHA.111.085787

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：2363 / 2373

页数：11

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