A general method for deprotection of N-toluenesulfonyl aziridines using sodium naphthalenide

被引：58

作者：

Bergmeier, SC ^{[1
]}

Seth, PP ^{[1
]}

机构：

[1] Ohio State Univ, Coll Pharm, Div Med Chem, Columbus, OH 43210 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 34期

关键词：

aziridine; protecting groups; sulfonamides;

D O I：

10.1016/S0040-4039(99)01210-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Deprotection of a variety of N-tosylaziridines with sodium naphthalenide provided the corresponding N-H-aziridines in excellent yield. No single electron transfer (SET) induced aziridine ring opening was seen under the conditions employed for the deprotection reaction. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：6181 / 6184

页数：4

共 29 条

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