Tin-based antitumour drugs

被引：288

作者：

Gielen, M

机构：

来源：

COORDINATION CHEMISTRY REVIEWS | 1996年 / 151卷

关键词：

antitumour drug; carcinoma; organotin compound; tin compound;

D O I：

10.1016/0010-8545(95)01216-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An overview is given of the results of the in vitro screening against MCF-7, a mammary tumour, and WiDr, a colon carcinoma, of several series of organotin compounds synthesized in the Free University of Brussels, Many di- and triorganotin compounds exhibit very promising in vitro antitumour activities, Di-n-butyltin bis(2,5-dihydroxybenzoate) is as active as cisplatin in vivo against murine Colon 26 carcinoma.

引用

页码：41 / 51

页数：11

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