Model for spatial microtubule oscillations

被引：7

作者：

Sept, D ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA

来源：

PHYSICAL REVIEW E | 1999年 / 60卷 / 01期

关键词：

D O I：

10.1103/PhysRevE.60.838

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

Under particular in vitro conditions, oscillating spatial and temporal waves of assembled microtubules can be observed. A reaction-diffusion model is presented to reproduce these results. This model is based on a set of chemical reaction equations and extended to include spatial dependence and diffusion. The basic properties of the model are presented and the results are demonstrated to connect the observable waves with turbidimetric measurements. The results of the model are consistent with experimental findings, [S1063-651X(99)05307-6].

引用

页码：838 / 841

页数：4

共 17 条

[1] A SEMI-IMPLICIT MIDPOINT RULE FOR STIFF SYSTEMS OF ORDINARY DIFFERENTIAL-EQUATIONS [J].

BADER, G ;

DEUFLHARD, P .

NUMERISCHE MATHEMATIK, 1983, 41 (03) :373-398

[2] SYNCHRONOUS OSCILLATIONS IN MICROTUBULE POLYMERIZATION [J].

CARLIER, MF ;

MELKI, R ;

PANTALONI, D ;

HILL, TL ;

CHEN, Y .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (15) :5257-5261

[3] THEORETICAL-STUDIES ON OSCILLATIONS IN MICROTUBULE POLYMERIZATION [J].

CHEN, YD ;

HILL, TL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (23) :8419-8423

[4] STOCHASTIC DYNAMICS OF MICROTUBULES - A MODEL FOR CAPS AND CATASTROPHES [J].

FLYVBJERG, H ;

HOLY, TE ;

LEIBLER, S .

PHYSICAL REVIEW LETTERS, 1994, 73 (17) :2372-2375

[5] Collective oscillations in microtubule growth [J].

Houchmandzadeh, B ;

Vallade, M .

PHYSICAL REVIEW E, 1996, 53 (06) :6320-6324

[6] Modeling microtubule oscillations [J].

Jobs, E ;

Wolf, DE ;

Flyvbjerg, H .

PHYSICAL REVIEW LETTERS, 1997, 79 (03) :519-522

[7] TUBULIN OLIGOMERS AND MICROTUBULE OSCILLATIONS - ANTAGONISTIC ROLE OF MICROTUBULE STABILIZERS AND DESTABILIZERS [J].

LANGE, G ;

MANDELKOW, EM ;

JAGLA, A ;

MANDELKOW, E .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1988, 178 (01) :61-69

[8] SPATIAL PATTERNS FROM OSCILLATING MICROTUBULES [J].

MANDELKOW, E ;

MANDELKOW, EM ;

HOTANI, H ;

HESS, B ;

MULLER, SC .

SCIENCE, 1989, 246 (4935) :1291-1293

[9] UNSTAINED MICROTUBULES STUDIES BY CRYO-ELECTRON MICROSCOPY - SUBSTRUCTURE, SUPERTWIST AND DISASSEMBLY [J].

MANDELKOW, EM ;

MANDELKOW, E .

JOURNAL OF MOLECULAR BIOLOGY, 1985, 181 (01) :123-135

[10]

MARX A, 1994, EUR BIOPHYS J BIOPHY, V22, P405, DOI 10.1007/BF00180162

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