Studies on lactams .102. Environ-friendly approaches to densely functionalized beta-lactams

被引：47

作者：

Jayaraman, M ^{[1
]}

Manhas, MS ^{[1
]}

Bose, AK ^{[1
]}

机构：

[1] STEVENS INST TECHNOL,DEPT CHEM & CHEM ENGN,HOBOKEN,NJ 07030

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 05期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(96)02421-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient approach to densely functionalized alpha-allyl-beta-lactams has been developed using organometallic reagents and alpha-keto-beta-lactams. Indium mediated Barbier reaction in aqueous media proceeded with a higher level of diastereoselectivity and chemical yield than zinc mediated Barbier reaction in anhydrous organic solvents. (C) 1997, Elsevier Science Ltd.

引用

页码：709 / 712

页数：4

共 19 条

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