Efficient and stereocontrolled synthesis of polysubstituted tetrahydropyrans by an allylstannylation/Bi(III)-promoted cyclisation strategy

被引：41

作者：

Leroy, B ^{[1
]}

Markó, IE ^{[1
]}

机构：

[1] Univ Catholique Louvain, Dept Chim, B-1348 Louvain, Belgium

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 49期

关键词：

allylation; tin; cyclisation; Sakurai reactions; carbamate; bismuth;

D O I：

10.1016/S0040-4039(01)01836-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel sequence, involving the condensation between a highly functionalised allylstannane and various aldehydes, followed by a bismuth triflate-promoted intramolecular Sakurai cyclisation (IMSC) of the resulting homoallylic alcohols, allows a rapid and stereocontrolled access to a range of polysubstituted tetrahydropyrans. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：8685 / 8688

页数：4

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