Building Molecular Complexity via Tandem Ru-catalyzed Isomerization/C-H Activation

被引：38

作者：

Bartoszewicz, Agnieszka ^{[1
]}

Martin-Matute, Belen ^{[1
]}

机构：

[1] Stockholm Univ, Dept Organ Chem, Arrhenius Lab, S-10691 Stockholm, Sweden

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 08期

基金：

瑞典研究理事会;

关键词：

C-BOND FORMATION; DIRECT ARYLATION; ALLYLIC ALCOHOLS; FUNCTIONALIZATION; KETONES;

D O I：

10.1021/ol900243x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A tandem isomerization/C-H activation of allylic alcohols was performed using a catalytic amount of RUCl2(PPh3)(3). A variety of ortho alkylated ketones have been obtained in excellent yields. This tandem process relies on an in situ generation of a carbonyl functional group that directs the ortho C-H bond activation.

引用

页码：1749 / 1752

页数：4

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