A concise total synthesis of naamidine A

被引：47

作者：

Aberle, NS ^{[1
]}

Lessene, G ^{[1
]}

Watson, KG ^{[1
]}

机构：

[1] Walter & Eliza Hall Inst Med Res, Med Chem Grp, Ctr Biotechnol, Bundoora, Vic 3086, Australia

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 03期

关键词：

D O I：

10.1021/ol052568o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A total synthesis of naamidine A is reported. Key benefits of the described pathway include its brevity, its synthetic ease, and its flexibility with respect to the preparation of analogues. Formation of the 2-aminoimidazole core is achieved by condensation of the appropriate alpha-aminoketone with cyanamide.

引用

页码：419 / 421

页数：3

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