Elite Suppression of HIV-1 Replication

被引：15

作者：

Blankson, Joel N. ^{[1
]}

Siliciano, Robert F. ^{[1
,2
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA

[2] Howard Hughes Med Inst, Baltimore, MD 21205 USA

来源：

IMMUNITY | 2008年 / 29卷 / 06期

关键词：

D O I：

10.1016/j.immuni.2008.12.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Rare HIV-1-infected individuals are able to control viral replication without antiretroviral therapy. In this issue of Immunity, Migueles et al. (2008) show that HIV-1-specific CD8(+) T cells from these individuals effectively suppress viral replication by granzyme B-mediated killing of target cells.

引用

页码：845 / 847

页数：3

共 10 条

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