Biosensors for the detection of bacteria

被引:100
作者
Deisingh, AK [1 ]
Thompson, M [1 ]
机构
[1] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada
关键词
biosensor; acoustic wave; electronic nose; bacterial detection; molecular beacon;
D O I
10.1139/w03-095
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review will consider the role of biosensors towards the detection of infectious bacteria, although noninfectious ones will be considered where necessary. Recently, there has been a heightened interest in developing rapid and reliable methods of detection. This is especially true for detection of organisms involved in bioterrorism, food poisoning, and clinical problems such as antibiotic resistance. Biosensors can assist in achieving these goals, and sensors using several of the different types of transduction modes are discussed: electrochemical, high frequency (surface acoustic wave), and optical. The paper concludes with a discussion of three areas that may make a great impact in the next few years: integrated (lab-on-a-chip) systems, molecular beacons, and aptamers.
引用
收藏
页码:69 / 77
页数:9
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