Synthesis of α-iodo-α,β-unsaturated ketones by the reaction of α-silyl-α,β-unsaturated ketones with ICl or ICl-AlCl3

被引：32

作者：

Alimardanov, A ^{[1
]}

Negishi, E ^{[1
]}

机构：

[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 20期

关键词：

alpha-iodo-alpha; beta-unsaturated ketones; alpha-silyl-alpha; ICl or ICl-AlCl3; iododesilylation;

D O I：

10.1016/S0040-4039(99)00635-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of alpha-silyl-alpha,beta-unsaturated enones, readily preparable as regio- and stereodefined compounds in high yields, with either 2 equiv. of ICl or one equiv. each of ICl and AlCl3 provides the corresponding alpha-iodo-alpha,beta-unsaturated enones in high yields. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：3839 / 3842

页数：4

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