Transient expression of a novel serine protease in the ectoderm of the ascidian Herdmania momus during development

被引：12

作者：

Arnold, JM

Kennett, C

Degnan, BM

Lavin, MF

机构：

[1] UNIV QUEENSLAND,DEPT ZOOL,BRISBANE,QLD,AUSTRALIA

[2] UNIV QUEENSLAND,ROYAL BRISBANE HOSP,DEPT SURG,BRISBANE,QLD 4029,AUSTRALIA

来源：

DEVELOPMENT GENES AND EVOLUTION | 1997年 / 206卷 / 07期

基金：

澳大利亚研究理事会;

关键词：

ascidian; serine protease; differential display; gene expression; in situ hybridization;

D O I：

10.1007/s004270050075

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We have studied gene expression during ascidian embryonic development using the technique of differential display and isolated partial cDNA sequences of 12 genes. Developmental regulation of these genes has been confirmed by northern hybridization analysis. Further cDNA cloning and sequence analysis of an mRNA that is present during gastrulation, neurulation and tailbud formation reveals that it encodes a novel serine protease containing a single kringle motif and catalytic domain. The spatial expression of this gene, designated Hmserp1, is restricted to precursor cells of the epidermis. The structure and expression of Hmsery1 is discussed in relation to possible functions during development.

引用

页码：455 / 463

页数：9

共 51 条

[1] DIFFERENTIAL DISPLAY ANALYSIS OF GENE-EXPRESSION IN DEVELOPING EMBRYOS OF XENOPUS-LAEVIS [J].