The Yin-Yang of cobalamin biochemistry

被引：134

作者：

Banerjee, R

机构：

[1] Biochemistry Department, University of Nebraska, Lincoln

来源：

CHEMISTRY & BIOLOGY | 1997年 / 4卷 / 03期

关键词：

D O I：

10.1016/S1074-5521(97)90286-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The cobalamins are B-12 cofactors with a reactive cobalt-carbon bond at their core and support the activity of two mammalian enzymes that are both medically important. The reactive organometallic bond of the cofactor can be cleaved either homolytically or heterolytically, but what determines how the enzymes control the fate of this bond?

引用

页码：175 / 186

页数：12

共 90 条

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