Recent advances in head and neck cancer

被引:724
作者
Haddad, Robert I. [1 ,2 ,3 ]
Shin, Dong M. [4 ]
机构
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Dept Med, Boston, MA 02115 USA
[3] Harvard Univ, Sch Med, Dept Med, Boston, MA USA
[4] Emory Univ, Dept Hematol Oncol, Winship Canc Inst, Atlanta, GA 30322 USA
关键词
D O I
10.1056/NEJMra0707975
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
There are more than half a million incident cases of squamous-cell carcinoma of the head and neck worldwide each year, primarily affecting the oropharynx, oral cavity, hypopharynx, and larynx. This review considers the biologic features of these tumors, including the role of human papillomavirus as a risk factor for cancer of the oropharynx. New therapies are considered, along with management approaches. Copyright © 2008 Massachusetts Medical Society.
引用
收藏
页码:1143 / 1154
页数:12
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