Ras superfamily and interacting proteins database

被引:10
作者
Bernards, Andre [1 ]
机构
[1] Massachusetts Gen Hosp, Canc Res Ctr, Charlestown, MA USA
来源
REGULATORS AND EFFECTORS OF SMALL GTPASES: RAS FAMILY | 2006年 / 407卷
关键词
D O I
10.1016/S0076-6879(05)07001-1
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
For geneticists and other researchers alike it is often useful to know how many related proteins might perform similar functions. With this in mind, a survey was performed to determine what proportion of human and Drosophila genes code for Ras superfamily members and their positive or negative regulators. Results indicate that just < 2% of genes in both genomes predict such proteins. A database was compiled to provide easy access to this information. This database also includes information on approximately 360 putative Ras superfamily effector proteins and may be a useful tool for those interested in GTPase biology.
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收藏
页码:1 / 9
页数:9
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