Male pseudohermaphroditism related to complications at conception, in early pregnancy or in prenatal growth

被引:23
作者
Francois, I [1 ]
van Helvoirt, M [1 ]
de Zegher, F [1 ]
机构
[1] Univ Leuven, Dept Pediat, Louvain, Belgium
关键词
male pseudohermaphroditism; fetus; growth; conception; pregnancy;
D O I
10.1159/000023321
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We examined whether male pseudohermaphroditism, when unexplained, is associated with reduced prenatal growth. Birth weight SD scores of 29 children with male pseudohermaphroditism were compared. The scores of children with an unexplained condition (median -2.1 SD) were found to be lower (p = 0.0001) than those of children with an explained condition (median -0.4 SD). In the majority of cases of unexplained male pseudohermaphroditism, there was a complicated history before conception or in early pregnancy. In conclusion, hitherto unexplained male pseudohermaphroditism was found to be associated with reduced prenatal growth and complications at conception or in early pregnancy.
引用
收藏
页码:91 / 95
页数:5
相关论文
共 24 条
[11]  
Fritz G, 1996, J REPROD FERTIL, V106, P63
[12]  
GRUMBACH MM, 1998, WILLIAMS TXB ENDOCRI, P1303
[13]   Insulin resistance in short children with intrauterine growth retardation [J].
Hofman, PL ;
Cutfield, WS ;
Robinson, EM ;
Bergman, RN ;
Menon, RK ;
Sperling, MA ;
Gluckman, PD .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (02) :402-406
[14]   Precocious pubarche, hyperinsulinism, and ovarian hyperandrogenism in girls:: Relation to reduced fetal growth [J].
Ibáñez, L ;
Potau, N ;
Francois, I ;
de Zegher, F .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1998, 83 (10) :3558-3562
[15]  
IBANEZ L, 1999, IN PRESS J CLIN ENDO
[16]  
Josso N, 1976, Recent Prog Horm Res, V33, P117
[17]  
KALLEN B, 1986, ACTA PAEDIATR SCAND, P1
[18]  
KALLEN B, 1982, ACTA PAEDIATR SC S, V293, P2
[19]   SILVER-RUSSELL SYNDROME - CASE WITH SEXUAL AMBIGUITY, AND A REVIEW OF LITERATURE [J].
MARKS, LJ ;
BERGESON, PS .
AMERICAN JOURNAL OF DISEASES OF CHILDREN, 1977, 131 (04) :447-451
[20]   ASSOCIATION OF PREGNANCY-INDUCED HYPERTENSION WITH DURATION OF SEXUAL COHABITATION BEFORE CONCEPTION [J].
ROBILLARD, PY ;
HULSEY, TC ;
PERIANIN, J ;
JANKY, E ;
MIRI, EH ;
PAPIERNIK, E .
LANCET, 1994, 344 (8928) :973-975