Synthesis and biological evaluation of 4-alkoxy substituted trinems .1.

被引：11

作者：

Andreotti, D

Biondi, S

DiFabio, R

Donati, D

Piga, E

Rossi, T

机构：

[1] Glaxo Wellcome S.p.A., Medicines Research Centre, 37138 Verona

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 16期

关键词：

D O I：

10.1016/0960-894X(96)00359-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Synthesis of new 4-alkoxy substituted trinems 4, 5, 6, 7 and 8 together with their antibacterial profiles compared to imipenem and GV104326 (2) are described. The good antibacterial profile observed for derivatives 4-7 encouraged further exploration of these derivatives. Copyright (C) 1996 Elsevier Science Ltd.

引用

页码：2019 / 2024

页数：6

共 18 条

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