Cobalt-55 positron emission tomography in recurrent ischaemic stroke

被引：19

作者：

De Reuck, J

Santens, P

Keppens, J

De Bleecker, J

Strijckmans, K

Goethals, P

Lemahieu, I

Korf, J

机构：

[1] State Univ Ghent Hosp, PET Ctr UZ RUG, B-9000 Ghent, Belgium

[2] State Univ Ghent Hosp, Dept Neurol, B-9000 Ghent, Belgium

[3] State Univ Ghent, Inst Nucl Sci, Analyt Chem Lab, B-9000 Ghent, Belgium

[4] State Univ Ghent, Dept Elect & Informat Syst, B-9000 Ghent, Belgium

[5] Univ Groningen Hosp, Dept Biol Psychiat, Groningen, Netherlands

来源：

CLINICAL NEUROLOGY AND NEUROSURGERY | 1999年 / 101卷 / 01期

关键词：

positron emission tomography; Cobalt-55; recurrent stroke;

D O I：

10.1016/S0303-8467(98)00076-6

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The present study investigates if Cobalt-55 (Co-55) positron emission tomography (PET) allows us to distinguish and detect recent, recurrent strokes in patients who had already suffered a previous infarct in the same vascular territory. Fourteen patients with recurrent strokes underwent a Co-55 PET scan of the brain. Recently infarcted areas, less than 2 months old, had a high Co-55 uptake ratio, whereas infarcts of 6 months to 1 year had an uptake ratio comparable to normal brain tissue. In infarcts older than 2 years the Co-55 uptake ratio was decreased compared to the control values. The evolution in Co-55 uptake ratios with time can be explained by the dynamics of the inflammatory response within the infarct core. Co-55 PET allows to demonstrate stroke recurrence and suggests that single photon emission tomography, using Co-57 as the tracer, could be a more easy alternative to be used in routine neurological practice. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：15 / 18

页数：4

共 15 条

[11] Cobalt-57 as a SPET tracer in the visualization of ischaemic brain damage in patients with middle cerebral artery stroke [J].

Stevens, H ;

Knollema, S ;

Piers, DA ;

Van de Wiele, C ;

Jansen, HML ;

De Jager, AEJ ;

De Reuck, J ;

Dierckx, RA ;

Korf, J .

NUCLEAR MEDICINE COMMUNICATIONS, 1998, 19 (06) :573-580

[12]

Stevens H, 1998, J NUCL MED, V39, P495

[13]

Stevens H, 1997, ACTA NEUROL BELG, V97, P172

[14]

STEVENS H, 1996, CLIN PHARM CEREBRAL, P31

[15] LEUKOCYTE INFILTRATION IN ACUTE HEMISPHERIC ISCHEMIC STROKE [J].

WANG, PY ;

KAO, CH ;

MUI, MY ;

WANG, SJ .

STROKE, 1993, 24 (02) :236-240

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