Microbial adhesion in flow displacement systems

被引:214
作者
Busscher, HJ [1 ]
van der Mei, HC [1 ]
机构
[1] Univ Groningen, Med Ctr, Dept Biomed Engn, NL-9700 AD Groningen, Netherlands
关键词
D O I
10.1128/CMR.19.1.127-141.2006
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Flow displacement systems are superior to many other (static) systems for studying microbial adhesion to surfaces because mass transport and prevailing shear conditions can be adequately controlled and notoriously ill-defined slight rinsing steps to remove so-called "loosely adhering organisms" can be avoided. In this review, we present the basic background required to calculate mass transport and shear rates in flow displacement systems, focusing on the parallelplate flow chamber as an example. Critical features in the design of flow displacement systems are discussed, as well as different strategies for data analysis. Finally, selected examples of working with flow displacement systems are given for diverse biomedical applications.
引用
收藏
页码:127 / +
页数:16
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