Gain-of-function STAT1 mutations are associated with PD-L1 overexpression and a defect in B-cell survival

被引：84

作者：

Romberg, Neil ^{[1
]}

Morbach, Henner ^{[2
]}

Lawrence, Monica G. ^{[4
]}

Kim, Sanghyun ^{[3
,6
]}

Kang, Insoo ^{[3
]}

Holland, Steven M. ^{[5
]}

Milner, Joshua D. ^{[4
]}

Meffre, Eric ^{[2
]}

机构：

[1] Yale Univ, Sch Med, Dept Pediat, Div Allergy & Clin Immunol, New Haven, CT 06510 USA

[2] Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT USA

[3] Yale Univ, Sch Med, Dept Internal Med, New Haven, CT 06510 USA

[4] NIAID, Lab Allerg Dis, NIH, Bethesda, MD 20892 USA

[5] NIAID, Lab Clin Infect Dis, NIH, Bethesda, MD 20892 USA

[6] Kangwon Natl Univ, Coll Med, Chunchon, South Korea

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2013年 / 131卷 / 06期

关键词：

CHRONIC MUCOCUTANEOUS CANDIDIASIS; APOPTOSIS; INDUCTION; TRANS;

D O I：

10.1016/j.jaci.2013.01.004

中图分类号：

R392 [医学免疫学];

学科分类号：

100108 [医学免疫学];

摘要：

[No abstract available]

引用

页码：1691 / 1693

页数：3

共 7 条

[1]

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21(WAF1/CIP1) mediated by STAT1 [J].

Chin, YE ;

Kitagawa, M ;

Su, WCS ;

You, ZH ;

Iwamoto, Y ;

Fu, XY .

SCIENCE, 1996, 272 (5262) :719-722

[2]

Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1 [J].

Hirahara, Kiyoshi ;

Ghoreschi, Kamran ;

Yang, Xiang-Ping ;

Takahashi, Hayato ;

Laurence, Arian ;

Vahedi, Golnaz ;

Sciume, Giuseppe ;

Hall, Aisling O'Hara ;

Dupont, Christopher D. ;

Francisco, Loise M. ;

Chen, Qian ;

Tanaka, Masao ;

Kanno, Yuka ;

Sun, Hong-Wei ;

Sharpe, Arlene H. ;

Hunter, Christopher A. ;

O'Shea, John J. .

IMMUNITY, 2012, 36 (06) :1017-1030

[3]

Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis [J].

Liu, Luyan ;

Okada, Satoshi ;

Kong, Xiao-Fei ;

Kreins, Alexandra Y. ;

Cypowyj, Sophie ;

Abhyankar, Avinash ;

Toubiana, Julie ;

Itan, Yuval ;

Audry, Magali ;

Nitschke, Patrick ;

Masson, Cecile ;

Toth, Beata ;

Flatot, Jerome ;

Migaud, Melanie ;

Chrabieh, Maya ;

Kochetkov, Tatiana ;

Bolze, Alexandre ;

Borghesi, Alessandro ;

Toulon, Antoine ;

Hiller, Julia ;

Eyerich, Stefanie ;

Eyerich, Kilian ;

Gulacsy, Vera ;

Chernyshova, Ludmyla ;

Chernyshov, Viktor ;

Bondarenko, Anastasia ;

Cortes Grimaldo, Rosa Maria ;

Blancas-Galicia, Lizbeth ;

Madrigal Beas, Ileana Maria ;

Roesler, Joachim ;

Magdorf, Klaus ;

Engelhard, Dan ;

Thumerelle, Caroline ;

Burgel, Pierre-Regis ;

Hoernes, Miriam ;

Drexel, Barbara ;

Seger, Reinhard ;

Kusuma, Theresia ;

Jansson, Annette F. ;

Sawalle-Belohradsky, Julie ;

Belohradsky, Bernd ;

Jouanguy, Emmanuelle ;

Bustamante, Jacinta ;

Bue, Melanie ;

Karin, Nathan ;

Wildbaum, Gizi ;

Bodemer, Christine ;

Lortholary, Olivier ;

Fischer, Alain ;

Blanche, Stephane .

JOURNAL OF EXPERIMENTAL MEDICINE, 2011, 208 (08) :1635-1648

[4]

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome [J].

Milner, Joshua D. ;

Brenchley, Jason M. ;

Laurence, Arian ;

Freeman, Alexandra F. ;

Hill, Brenna J. ;

Elias, Kevin M. ;

Kanno, Yuka ;

Spalding, Christine ;

Elloumi, Houda Z. ;

Paulson, Michelle L. ;

Davis, Joie ;

Hsu, Amy ;

Asher, Ava I. ;

O'Shea, John ;

Holland, Steven M. ;

Paul, William E. ;

Douek, Daniel C. .

NATURE, 2008, 452 (7188) :773-U11

[5]

Human B-cell lymphoma cell lines are highly sensitive to apoptosis induced by all-trans retinoic acid and interferon-γ [J].

Niitsu, N ;

Higashihara, M ;

Honma, Y .

LEUKEMIA RESEARCH, 2002, 26 (08) :745-755

[6]

STAT1-induced apoptosis is mediated by caspases 2, 3, and 7 [J].

Sironi, JJ ;

Ouchi, T .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (06) :4066-4074

[7]

STAT1 Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis [J].

van de Veerdonk, Frank L. ;

Plantinga, Theo S. ;

Hoischen, Alexander ;

Smeekens, Sanne P. ;

Joosten, Leo A. B. ;

Gilissen, Christian ;

Arts, Peer ;

Rosentul, Diana C. ;

Carmichael, Andrew J. ;

Smits-van der Graaf, Chantal A. A. ;

Kullberg, Bart Jan ;

van der Meer, Jos W. M. ;

Lilic, Desa ;

Veltman, Joris A. ;

Netea, Mihai G. .

NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (01) :54-61

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