Effect of Cu2+-ions on semiconductor properties of synthetic DOPA melanin polymer

被引：26

作者：

Jastrzebska, MM ^{[1
]}

Isotalo, H ^{[1
]}

Paloheimo, J ^{[1
]}

Stubb, H ^{[1
]}

Pilawa, B ^{[1
]}

机构：

[1] VTT ELECT ELECT MAT & COMPONENTS,SF-02150 ESPOO,FINLAND

来源：

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION | 1996年 / 7卷 / 09期

关键词：

melanin; metal complexation; organic semiconductor; bipolaron; culture substratum;

D O I：

10.1163/156856296X00129

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The purpose of the present study was to examine semiconductor properties of synthetic DOPA melanin, which are basic for future biological applications. DC conductivity, electron spin resonance (ESR),and atomic absorption spectroscopy (AAS) measurements have been performed to investigate the effect of Cu2+-ions on the semiconductor properties of melanin polymer synthesized from DOPA (3,4-dihydroxyphenylalanine). DOPA melanin - Cu2+ complexes examined show the decrease of both thermal activation energy Delta E(a) and pre-exponential factor sigma(0) values upon doping. At the same time no substantial changes in conductivity at 293 K have been observed. Formation of bipolaron states due to chelation of copper ions by melanin ortho-semiquinones has been postulated. The Meyer-Neldel rule with a characteristic temperature T-0 equal to 298 K and possible physiological implication of this fact are discussed. These data suggest, that DOPA melanin polymer could be useful as a type of culture substratum.

引用

页码：781 / 793

页数：13

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