At-Cu-Fe quasicrystal/ultra-high molecular weight polyethylene composites as biomaterials for acetabular cup prosthetics

被引：84

作者：

Anderson, BC

Bloom, PD

Baikerikar, KG

Sheares, VV

Mallapragada, SK

机构：

[1] Iowa State Univ Sci & Technol, Dept Chem Engn, Ames, IA 50011 USA

[2] Iowa State Univ Sci & Technol, Dept Chem, Ames, IA 50011 USA

[3] US DOE, Ames Lab, Ames, IA 50011 USA

来源：

BIOMATERIALS | 2002年 / 23卷 / 08期

基金：

美国能源部;

关键词：

quasicrystal; reduced wear; polymer composite; joint replacement; biocompatible;

D O I：

10.1016/S0142-9612(01)00301-5

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Polymer composites of Al-Cu Fe quasicrystals and ultra-high molecular weight polyethylene (UHMWPE) were investigated for use in acetabular cup prosthetics. The wear properties of the Al Cu-Fe/UHMWPE samples and a 440 steel ball counterface were measured. The mechanical strength of the Al Cu Fe/UHMWPE composites was compared to UHMWPE and alumina/UHMWPE. The biocompatibility of the composite material was tested using a direct contact cytotoxicity assay. At-Cu-Fe/UHMWPE demonstrated lower volume loss after wear and higher mechanical strength than UHMWPE. This composite material also showed no increase in counterface wear or cytotoxicity relative to UHMWPE. These combined results demonstrate that Al Cu Fe/UHMWPE composites are promising candidate materials for acetabular cup prosthetics. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1761 / 1768

页数：8

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