Only connect: Linking meiotic DNA replication to chromosome dynamics

被引:27
作者
Forsburg, SL [1 ]
机构
[1] Salk Inst Biol Studies, Mol & Cell Biol Lab, La Jolla, CA 92037 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
D O I
10.1016/S1097-2765(02)00508-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The process of meiosis reduces a diploid cell to four haploid gametes and is accompanied by extensive recombination. Thus, chromosome dynamics in meiosis are significantly different than in mitotic cells. This review analyzes unique features of meiotic DNA replication and describes how it affects subsequent recombination and chromosome segregation.
引用
收藏
页码:703 / 711
页数:9
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