Oligonephropathy, developmental programming and nutritional management of low-gestation newborns

被引:11
作者
Yeung, MY [1 ]
机构
[1] Childrens Hosp, Dept Pharm, Westmead, NSW 2145, Australia
关键词
extreme prematurity; developmental programming; protein under-nutrition; oligonephropathy;
D O I
10.1080/08035250500440394
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Intrauterine growth retardation is associated with oligonephropathy and the risk of hypertension and renal disease in adulthood. Animal study data show that nephron density is directly related to protein nutrition status during nephrogenesis. Among infants born at low gestation, postnatal growth retardation and major deficits in energy and protein intake have been reported. Conclusion: Since nephrogenesis occurs mainly in late gestation, increasing protein intake during nephrogenesis could minimize the risk of long-term morbidities associated with oligonephropathy.
引用
收藏
页码:263 / 267
页数:5
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