Ischemic stroke and neurogenesis in the subventricular zone

被引:153
作者
Zhang, Rui Lan [1 ]
Zhang, Zheng Gang [1 ]
Chopp, Michael [1 ,2 ]
机构
[1] Henry Ford Hlth Sci Ctr, Dept Neurol, Detroit, MI 48202 USA
[2] Oakland Univ, Dept Phys, Rochester, MI 48309 USA
关键词
ischemic stroke; subventricular zone; neurogenesis;
D O I
10.1016/j.neuropharm.2008.05.027
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The subventricular zone (SVZ) of the lateral ventricle contains neural stem and progenitor cells that generate neuroblasts, which migrate to the olfactory bulb where they differentiate into interneurons. Ischemic stroke induces neurogenesis in the SVZ and these cells migrate to the boundary of the ischemic lesion. This article reviews current data on cytokinetics, signaling pathways and vascular niche that are involved in processes of proliferation, differentiation, and migration of neural progenitor cells after stroke. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:345 / 352
页数:8
相关论文
共 126 条
[51]  
Liu JL, 1998, J NEUROSCI, V18, P7768
[52]   Comparison of In vivo and in vitro gene expression profiles in subventricular zone neural progenitor cells from the adult mouse after middle cerebral artery occlusion [J].
Liu, X. S. ;
Zhang, Z. G. ;
Zhang, R. L. ;
Gregg, S. R. ;
Meng, H. ;
Chopp, M. .
NEUROSCIENCE, 2007, 146 (03) :1053-1061
[53]   Adult neurogenesis and functional plasticity in neuronal circuits [J].
Lledo, PM ;
Alonso, M ;
Grubb, MS .
NATURE REVIEWS NEUROSCIENCE, 2006, 7 (03) :179-193
[54]   Chain migration of neuronal precursors [J].
Lois, C ;
GarciaVerdugo, JM ;
AlvarezBuylla, A .
SCIENCE, 1996, 271 (5251) :978-981
[55]   LONG-DISTANCE NEURONAL MIGRATION IN THE ADULT MAMMALIAN BRAIN [J].
LOIS, C ;
ALVAREZBUYLLA, A .
SCIENCE, 1994, 264 (5162) :1145-1148
[56]   The aging neurogenic subventricular zone [J].
Luo, J ;
Daniels, SB ;
Lennington, JB ;
Notti, RQ ;
Conover, JC .
AGING CELL, 2006, 5 (02) :139-152
[57]   RESTRICTED PROLIFERATION AND MIGRATION OF POSTNATALLY GENERATED NEURONS DERIVED FROM THE FOREBRAIN SUBVENTRICULAR ZONE [J].
LUSKIN, MB .
NEURON, 1993, 11 (01) :173-189
[58]   Neuronal progenitor cells derived from the anterior subventricular zone of the neonatal rat forebrain continue to proliferate in vitro and express a neuronal phenotype [J].
Luskin, MB ;
Zigova, T ;
Soteres, BJ ;
Stewart, RR .
MOLECULAR AND CELLULAR NEUROSCIENCE, 1997, 8 (05) :351-366
[59]   Increased generation of neuronal progenitors after ischemic injury in the aged adult human forebrain [J].
Macas, Jadranka ;
Nern, Christian ;
Plate, Karl H. ;
Momma, Stefan .
JOURNAL OF NEUROSCIENCE, 2006, 26 (50) :13114-13119
[60]   Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice [J].
Maslov, AY ;
Barone, TA ;
Plunkett, RJ ;
Pruitt, SC .
JOURNAL OF NEUROSCIENCE, 2004, 24 (07) :1726-1733