A suite of skeletons and frozen carcasses of upper Pleistocene mammals from Yakutia (Sakha Republic, Russia) has been analyzed for their stable isotopic abundances in carbon and nitrogen. Results from bone collagen and soft tissues have been compared. The samples studied belong to herbivorous (mammoths, woolly rhinoceros, horse, bison, muskox) and carnivorous (wolf, lion) species. Bone collagen of herbivorous and carnivorous modern mammals from the same region have been analyzed for comparison. The bone samples exhibit a very good preservation of collagen. The isotopic enrichment between herbivorous and carnivorous species is similar in modern and Pleistocene specimens, except for the mammoths, which show more negative delta(13)C values and higher delta(15)N values of collagen relative to other herbivorous species. A similar isotopic pattern can be seen in upper Pleistocene mammoths from Alaska, and this pattern suggests a paleobiological significance.