The use of solubility parameters in pharmaceutical dosage form design

被引：244

作者：

Hancock, BC

York, P

Rowe, RC

机构：

[1] UNIV BRADFORD,SCH PHARM,BRADFORD BD7 1DP,W YORKSHIRE,ENGLAND

[2] ZENECA PHARMACEUT,MACCLESFIELD,CHESHIRE,ENGLAND

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1997年 / 148卷 / 01期

关键词：

cohesive energy density; solubility parameter; interaction; polarity; formulation;

D O I：

10.1016/S0378-5173(96)04828-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The use and potential of solubility parameters for pharmaceutical dosage form design are reviewed in this paper. Specific reference is given to the development of the approach, its previous usage and likely future applications. The advantages, assumptions and limitations of this type of approach are also described. (C) 1997 Elsevier Science B.V.

引用

页码：1 / 21

页数：21

共 109 条

[41] DRUG TRANSPORT THROUGH MODEL MEMBRANES AND ITS CORRELATION WITH SOLUBILITY PARAMETERS [J].

KHALIL, SA ;

MARTIN, AN .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1967, 56 (10) :1225-+

[42] DETERMINATION OF THE SOLUBILITY PARAMETER OF SOYBEAN OIL BY INVERSE GAS-CHROMATOGRAPHY [J].

KING, JW .

FOOD SCIENCE AND TECHNOLOGY-LEBENSMITTEL-WISSENSCHAFT & TECHNOLOGIE, 1995, 28 (02) :190-195

[43] DETERMINATION OF SOLUBILITY PARAMETERS OF SOLVENTS AND POLYMERS BY MEANS OF CORRELATIONS WITH OTHER PHYSICAL QUANTITIES [J].

KOENHEN, DM ;

SMOLDERS, CA .

JOURNAL OF APPLIED POLYMER SCIENCE, 1975, 19 (04) :1163-1179

[44] THE CORRELATION OF MEMBRANE PERMSELECTIVITY WITH HILDEBRAND SOLUBILITY PARAMETERS [J].

LAPACK, MA ;

TOU, JC ;

MCGUFFIN, VL ;

ENKE, CG .

JOURNAL OF MEMBRANE SCIENCE, 1994, 86 (03) :263-280

[45] RELATIONSHIPS BETWEEN SURFACE WETTABILITY AND GLASS TEMPERATURES OF HIGH POLYMERS [J].

LEE, LH .

JOURNAL OF APPLIED POLYMER SCIENCE, 1968, 12 (04) :719-&

[46] A SURFACE-ENERGY ANALYSIS OF MUCOADHESION .2. PREDICTION OF MUCOADHESIVE PERFORMANCE BY SPREADING COEFFICIENTS [J].

LEHR, CM ;

BODDE, HE ;

BOUWSTRA, JA ;

JUNGINGER, HE .

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 1993, 1 (01) :19-30

[47] SOLUTION THERMODYNAMICS OF SOME POTENTIALLY LONG-ACTING NORETHINDRONE DERIVATIVES .2. SOLUTIONS IN 2,2,4-TRIMETHYLPENTANE (ISO-OCTANE) [J].

LEWIS, GA ;

ENEVER, RP .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1979, 3 (4-5) :275-288

[48]

LHOEST G, 1972, PHARM ACTA HELV, V48, P547

[49]

Lin H.-M., 1992, THESIS ST JOHNS U NE

[50] SOME PHYSICAL PROPERTIES OF SOAP/SOLVENT SYSTEMS AND THEIR RELATION TO SOLUBILITY PARAMETER OF SOLVENT [J].

LITTLE, RC .

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1966, 21 (03) :266-&

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