MHC class II molecules: Transport pathways for antigen presentation

被引：5

作者：

Wubbolts, R

FernandezBorja, M

Neefjes, J

机构：

[1] Division of Cellular Biochemistry, Netherlands Cancer Institute, 1066 CX Amsterdam

来源：

TRENDS IN CELL BIOLOGY | 1997年 / 7卷 / 03期

关键词：

D O I：

10.1016/S0962-8924(97)01000-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

During biosynthesis, MHC class II molecules travel through the endocytic pathway and interact with antigenic peptides before their stable insertion in the plasma membrane. The process of class II association with these peptides and their final deposition at the cell surface are essential steps in boosting specific antibody responses. Therefore, the study of class II molecules is important in understanding how cell-biological events can direct an immune response.

引用

收藏

页码：115 / 118

页数：4

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