Naturally circulating dendritic cells to vaccinate cancer patients

被引:32
作者
Bol, Kalijn F. [1 ,2 ]
Tel, Jurjen [1 ]
de Vries, I. Jolanda M. [1 ,2 ]
Figdor, Carl G. [1 ]
机构
[1] Radboud Univ Nijmegen, Med Ctr, Nijmegen Ctr Mol Life Sci, Dept Tumor Immunol, NL-6525 ED Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Med Ctr, Dept Med Oncol, NL-6525 ED Nijmegen, Netherlands
关键词
cancer immunotherapy; dendritic-cell targeting; dendritic-cell vaccination; myeloid dendritic cells; plasmacytoid dendritic cells;
D O I
10.4161/onci.23431
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
Dendritic cell-based immunotherapy is a promising strategy against cancer that appears to be feasible, safe and to induce potent tumor-specific immune responses. The use of naturally circulating dendritic cells (DCs), rather than cultured monocyte-derived DCs, might constitute the next logical step to translate anticancer immune responses into long-lasting clinical benefits.
引用
收藏
页数:3
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