Levels of chloroquine resistance in Plasmodium falciparum are determined by loci other than pfcrt and pfmdr1

被引：44

作者：

Chen, NH

Russell, B

Fowler, E

Peters, J

Cheng, Q

机构：

[1] Australian Army Malaria Inst, Dept Parasitol, Enoggera, Qld 4051, Australia

[2] Queensland Inst Med Res, Brisbane, Qld 4006, Australia

来源：

JOURNAL OF INFECTIOUS DISEASES | 2002年 / 185卷 / 03期

关键词：

D O I：

10.1086/338470

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：405 / 406

页数：2

共 4 条

[1] High-level chloroquine resistance in sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance gene pfmdr1 [J].

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[2] Sequence polymorphisms in pfcrt are strongly associated with chloroquine resistance in Plasmodium falciparum [J].

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Staley, J ;

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Nasveld, P ;

Cheng, Q .

JOURNAL OF INFECTIOUS DISEASES, 2001, 183 (10) :1543-1545

[3] The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin [J].

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Warhurst, DC .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2000, 108 (01) :13-23

[4] Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum [J].

Reed, MB ;

Saliba, KJ ;

Caruana, SR ;

Kirk, K ;

Cowman, AF .

NATURE, 2000, 403 (6772) :906-909

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