Particle size effect on phase and magnetic properties of polymer-coated magnetic nanoparticles

被引：57

作者：

Balakrishnan, Srinivasan ^{[1
]}

Bonder, Michael J. ^{[1
]}

Hadjipanayis, George C. ^{[1
]}

机构：

[1] Univ Delaware, Dept Phys & Astron, Newark, DE 19711 USA

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2009年 / 321卷 / 02期

基金：

美国国家科学基金会;

关键词：

Magnetic nanoparticles; Polymer coating; Hyperthermia; Particle size distribution; Dark-field microscopy; BIOMEDICAL APPLICATIONS; REDUCTION;

D O I：

10.1016/j.jmmm.2008.08.055

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Polymer-coated magnetic nanoparticles are hi-tech materials with ample applications in the field of biomedicine for the treatment of cancer and targeted drug delivery. In this study, magnetic nanoparticles were synthesized by chemical reduction of FeCl(2) solution with sodium borohydride and coated with amine-terminated polyethylene glycol (aPEG). By varying the concentration of the reactants, the particle size and the crystallinity of the particles were varied. The particle size was found to increase from 6 to 20 nm and the structure becomes amorphous-like with increase in the molar concentration of the reactant. The magnetization at 1 T field (M(1T)) for all samples is >45 emu/g while the coercivity is in the range of 100-350 Oe. When the ethanol-suspended particles are subjected to an alternating magnetic field of 4 Oe at 500 kHz, the temperature is increased to a maximum normalized temperature (3.8 degrees C/mg) with decreasing particle size. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：117 / 122

页数：6

共 14 条

[1] Size dependent in-vitro heating with polyethylene glycol coated magnetic nanoparticles [J].

Bonder, M. J. ;

Gallo, D. ;

Srinivasan, B. ;

Hadjipanayis, G. C. .

IEEE TRANSACTIONS ON MAGNETICS, 2007, 43 (06) :2457-2458

[2] In vitro heating with polyethylene glycol coated Fe nanoparticles [J].

Bonder, M. J. ;

Srinivasan, B. ;

Poirier, G. ;

Moriyama, T. ;

Kiick, K. L. ;

Hadjipanayis, G. C. .

IEEE TRANSACTIONS ON MAGNETICS, 2006, 42 (10) :3602-3604

[3] AMORPHOUS TRANSITION-METAL BORON ULTRAFINE PARTICLES PREPARED BY CHEMICAL METHODS [J].

CORRIAS, A ;

ENNAS, G ;

MUSINU, A ;

MARONGIU, G ;

PASCHINA, G .

CHEMISTRY OF MATERIALS, 1993, 5 (12) :1722-1726

[4] MAGNETIC-PROPERTIES OF ULTRAFINE IRON PARTICLES [J].

GANGOPADHYAY, S ;

HADJIPANAYIS, GC ;

DALE, B ;

SORENSEN, CM ;

KLABUNDE, KJ ;

PAPAEFTHYMIOU, V ;

KOSTIKAS, A .

PHYSICAL REVIEW B, 1992, 45 (17) :9778-9787

[5] Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications [J].

Gupta, AK ;

Gupta, M .

BIOMATERIALS, 2005, 26 (18) :3995-4021

[6] A STUDY OF FE-NI-B ULTRAFINE ALLOY PARTICLES PRODUCED BY REDUCTION WITH BOROHYDRIDE [J].

HU, Z ;

HSIA, YF ;

ZHENG, JG ;

SHEN, JY ;

YAN, QJ ;

DAI, LM .

JOURNAL OF APPLIED PHYSICS, 1991, 70 (01) :436-438

[7] Magnetic fluid hyperthermia (MFH):: Cancer treatment with AC magnetic field induced excitation of biocompatible superparamagnetic nanoparticles [J].

Jordan, A ;

Scholz, R ;

Wust, P ;

Fähling, H ;

Felix, R .

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 1999, 201 :413-419

[8] In vitro characterization of movement, heating and visualization of magnetic nanoparticles for biomedical applications [J].

Kalambur, VS ;

Han, B ;

Hammer, BE ;

Shield, TW ;

Bischof, JC .

NANOTECHNOLOGY, 2005, 16 (08) :1221-1233

[9] MOSSBAUER-EFFECT IN SMALL PARTICLES [J].

MORUP, S .

HYPERFINE INTERACTIONS, 1990, 60 (1-4) :959-974

[10] Preparation of magnetic nanoparticles with large specific loss power for heating applications [J].

Müller, R ;

Hergt, R ;

Zeisberger, M ;

Gawalek, W .

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2005, 289 :13-16

← 1 2 →